HUMAN PLASMABLAST MIGRATION TOWARD CXCL12 REQUIRES GLUCOSE OXIDATION BY ENHANCED PYRUVATE DEHYDROGENASE ACTIVITY VIA AKT

Human Plasmablast Migration Toward CXCL12 Requires Glucose Oxidation by Enhanced Pyruvate Dehydrogenase Activity via AKT

Migration of human plasmablast to the bone marrow is essential for the final differentiation of plasma cells and maintenance of effective humoral immunity.This migration is controlled by CXCL12/CXCR4-mediated activation of the protein kinase AKT.Herein, we show that the CXCL12-induced migration of human plasmablasts is dependent on glucose oxidatio

read more

Canonical discrimination of the effect of a new broiler production facility on soil chemical profiles as related to current management practices.

The effect dirt-floored broiler houses have on the underlying native soil, and the potential for contamination of the ground water by leaching under the foundation, is an understudied area.This study examines alterations in fifteen quantitative soil parameters (Ca, Cu, electrical conductivity, Fe, K, Mg, Mn, Na, NO3, organic matter, P, pH, S, soil

read more

The Biomimetics of Mg2+-Concentration-Resolved Microenvironment for Bone and Cartilage Repairing Materials Design

With the increase in population aging, the tendency of osteochondral injury will be accelerated, and repairing materials are increasingly needed for the optimization of the regenerative processes in bone and cartilage recovery.The local environment of the injury sites and the deficiency of Mg2+ retards the AEG BS831410KM ProCombi Steam Oven repairi

read more

Links between sea surface temperature anomalies and seismic activity in the Red Sea across multiple temporal scales

Abstract This study evaluates the links between seismic activity and sea surface temperature (SST) variability in the Red Sea from 2003 to 2020.We utilized the Egyptian National Seismic Network (ENSN) and ISC-GEM Global Instrumental Earthquake Catalogue (version 9.0) provided by the Global Earthquake Risk Model (GEM) Organizations and the Moderate

read more

Navigating the evolution: a comprehensive review of sustainable finance in mergers and acquisitions [version 1; peer review: 2 approved]

Background The global shift in corporate philosophy from wealth maximization to share value creation has propelled sustainable finance into the forefront of research endeavours.Despite its significance, the realm of sustainable finance, especially in the context of mergers and acquisitions, remains relatively underexplored.Objective This research i

read more